Schistosomes in the Lung: Immunobiology and Opportunity
- Katie
- 0
Immunobiology and pathogenesis of hepatitis B virus an infection
Hepatitis B virus (HBV) is a non-cytopathic, hepatotropic virus with the potential to trigger a persistent an infection, finally resulting in cirrhosis and hepatocellular carcinoma.
Over the previous 4 a long time, the fundamental rules of HBV gene expression and replication in addition to the viral and host determinants governing an infection end result have been largely uncovered. Whereas HBV seems to induce little or no innate immune activation, the adaptive immune response mediates each viral clearance in addition to liver illness.
Right here, we evaluation our present information on the immunobiology and pathogenesis of HBV an infection, focusing particularly on the position of CD8+ T cells and on a number of current breakthroughs that problem present dogmas.
For instance, we now belief that HBV integration into the host genome usually serves as a related supply of hepatitis B floor antigen (HBsAg) expression throughout persistent an infection, probably triggering dysfunctional T cell responses and favouring detrimental immunopathology.
Additional, the distinctive haemodynamics and anatomy of the liver – and the adjustments they incessantly endure throughout illness development to liver fibrosis and cirrhosis – profoundly affect T cell priming, differentiation and performance.
We additionally focus on why therapeutic approaches that restrict the intrahepatic inflammatory processes triggered by HBV-specific T cells may be surprisingly helpful for sufferers with persistent an infection.
Human Testosterone ELISA Kit |
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EH4850 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.188 ng/ml |
Human SPOCK2(Testican-2) ELISA Kit |
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EH2271 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human TEX101(testis expressed 101) ELISA Kit |
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EH12903 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.188 ng/ml |
Human F-TESTO(Free Testoterone) ELISA Kit |
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EH3092 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human ApoB48 ELISA Kit |
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EH4928 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75 ng/ml |
Human APOM(Apolipoprotein M) ELISA Kit |
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EH2134 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human APOD(Apolipoprotein D) ELISA Kit |
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EH2135 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml |
Human ApoF(Apolipoprotein F) ELISA Kit |
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EH2657 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human APOE(Apolipoprotein E ) ELISA Kit |
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EH0549 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.75 ng/ml |
Human APOL1(Apolipoprotein L1) ELISA Kit |
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EH1181 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml |
Human ApoB100(Apolipoprotein B100) ELISA Kit |
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EH0074 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5 ng/ml |
Human APOA5(Apolipoprotein A-V) ELISA Kit |
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EH1952 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human APOA1(Apolipoprotein A-I ) ELISA Kit |
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EH0545 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human APOA4(Apolipoprotein A-IV) ELISA Kit |
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EH0618 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 2.813 ng/ml |
Human APOB(Apolipoprotein B-100) ELISA Kit |
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EH0620 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875 ng/ml |
Human APOA2(Apolipoprotein A-II) ELISA Kit |
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EH0633 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5 ng/ml |
Rat ApoC3(Apolipoprotein C3) ELISA Kit |
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ER0741 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 3.75 ng/ml |
Accu-Tell COVID-19 IgG/IgM Rapid Test |
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GEN-B352-20tests | Accu test | 20 tests | EUR 283.2 |
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus. |
Rabbit ApoC1(Apolipoprotein C1) ELISA Kit |
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ERB0012 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rabbit;Sensitivity: 0.094 ng/ml |
Monkey ApoC3(Apolipoprotein C3) ELISA Kit |
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EMK0008 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Ape;Sensitivity: 0.938 ng/ml |
Mouse APO-C1(Apolipoprotein C1) ELISA Kit |
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EM0844 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 37.5 ng/ml |
Mouse APO-C4(Apolipoprotein C4) ELISA Kit |
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EM0845 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml |
Human PDHA2(Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial) ELISA Kit |
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EH1149 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
T(Testosterone) ELISA Kit |
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EU0400 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 0.188 ng/ml |
Mouse Testosterone ELISA Kit |
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EM1850 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml |
Rat T(Testosterone) ELISA Kit |
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ER1462 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml |
Human BAX(Apoptosis regulator BAX) ELISA Kit |
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EH0669 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml |
Human APOH(Beta-2-glycoprotein 1 ) ELISA Kit |
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EH0531 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 28.125pg/ml |
Bovine T(Testosterone) ELISA Kit |
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EB0049 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Cattle;Sensitivity: 0.188 ng/ml |
Human APOA1BP(Apolipoprotein A-I-binding protein) ELISA Kit |
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EH1180 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human FASL(Factor Related Apoptosis Ligand) ELISA Kit |
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EH0127 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human SIVA1(Apoptosis regulatory protein Siva) ELISA Kit |
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EH2267 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.9pg/ml |
Human Apo A1-Ab(Anti-Apolipoprotein A1 Antibody) ELISA Kit |
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EH2655 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Sandwich ELISA, Double Antigen ;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml |
Human PAWR(PRKC apoptosis WT1 regulator protein) ELISA Kit |
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EH10908 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma) |
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GEN-402-25tests | All test | 25 tests | EUR 292.8 |
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus. |
Human FAIM3(Fas Apoptotic Inhibitory Molecule 3) ELISA Kit |
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EH3035 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human PUMA(P53 Upregulated Modulator of Apoptosis) ELISA Kit |
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EH0250 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human CD94 ELISA Kit |
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EH7228 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml |
Human NAIF1(Nuclear apoptosis-inducing factor 1) ELISA Kit |
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EH1223 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human TIGAR ELISA Kit |
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EH4927 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human CD226 ELISA Kit |
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EH7177 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml |
Human EPAC2 ELISA Kit |
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EH8258 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human APAF1(Apoptosis Protease Activating Factor 1) ELISA Kit |
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EH2654 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human TRIM14 ELISA Kit |
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EH13190 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human Spexin ELISA Kit |
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EH4349 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pg/ml |
Human Irisin ELISA Kit |
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EH4702 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human PRSS36 ELISA Kit |
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EH4924 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human SHARPIN ELISA Kit |
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EH12274 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human SERPIND1 ELISA Kit |
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EH12199 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human Thrombin ELISA Kit |
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EH4141 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human Asprosin ELISA Kit |
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EH4176 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human KITLG(Kit ligand ) ELISA Kit |
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EH0514 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human ASK-1(Apoptosis Signal Regulating Kinase 1) ELISA Kit |
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EH2670 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human Neopterin ELISA Kit |
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EH3413 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human CFLAR(CASP8 and FADD-like apoptosis regulator) ELISA Kit |
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EH1762 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.9pg/ml |
Human Calprotectin ELISA Kit |
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EH4140 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375 ng/ml |
Human Pre-S1 ELISA Kit |
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EH4111 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Qualitative ;Reacts with: Homo sapiens;Sensitivity: Qualitative |
Human EZR(Ezrin) ELISA Kit |
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EH1471 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human TTN(Titin) ELISA Kit |
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EH1877 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human KL(Klotho) ELISA Kit |
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EH2184 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pg/ml |
Human PP(Pepsin) ELISA Kit |
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EH3629 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
Human Rbx2(RNF7) ELISA Kit |
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EH4196 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human CRN(Corin) ELISA Kit |
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EH0097 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 45pg/ml |
Human FUR(Furin) ELISA Kit |
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EH0143 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human REN(Renin) ELISA Kit |
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EH0268 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human AGRN(Agrin) ELISA Kit |
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EH1477 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human NDP(Norrin) ELISA Kit |
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EH1664 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human MEFV(Pyrin) ELISA Kit |
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EH2102 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human NES(Nestin) ELISA Kit |
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EH2140 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human AFM(Afamin) ELISA Kit |
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EH2493 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml |
Human Des(Desmin) ELISA Kit |
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EH2944 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human Activin A ELISA Kit |
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EH0028 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
Human LN(Laminin) ELISA Kit |
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EH0214 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human LEP(Leptin) ELISA Kit |
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EH0216 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human MK(Midkine) ELISA Kit |
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EH0229 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human NDN(Necdin) ELISA Kit |
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EH0866 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human NOG(Noggin) ELISA Kit |
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EH1051 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human ELN(Elastin) ELISA Kit |
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EH1505 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.281 ng/ml |
Human GC(Glucagon) ELISA Kit |
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EH1944 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human ACR(Acrosin) ELISA Kit |
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EH2014 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 3.75mIU/ml |
Human RELN(Reelin) ELISA Kit |
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EH2121 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human APLN(Apelin) ELISA Kit |
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EH2174 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
Human OGN(Mimecan) ELISA Kit |
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EH2412 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human MTL(Motilin) ELISA Kit |
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EH3393 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human TRY(Trypsin) ELISA Kit |
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EH3915 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human OSX(Osterix) ELISA Kit |
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EH4043 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human Es(Estrogen) ELISA Kit |
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EH4184 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human OT(Oxytocin) ELISA Kit |
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EH4212 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human DCN(Decorin) ELISA Kit |
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EH0111 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.75 ng/ml |
Human LUM(Lumican) ELISA Kit |
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EH0220 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human INS(Insulin) ELISA Kit |
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EH0374 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human FE(Ferritin) ELISA Kit |
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EH0382 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human HCRT(Orexin) ELISA Kit |
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EH1045 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human Aldolase B ELISA Kit |
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EH4806 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.281 ng/ml |
Human SCT(Secretin) ELISA Kit |
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EH1210 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human BGN(Biglycan) ELISA Kit |
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EH1218 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human GAST(Gastrin) ELISA Kit |
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EH1397 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188pg/ml |
Human PRX(Periaxin) ELISA Kit |
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EH1492 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human OPTC(Opticin) ELISA Kit |
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EH1604 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.9pg/ml |
Human PLEC(Plectin) ELISA Kit |
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EH1770 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human FSCN1(Fascin) ELISA Kit |
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EH1915 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml |
Human VCL(Vinculin) ELISA Kit |
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EH1957 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human TNC(Tenascin) ELISA Kit |
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EH2027 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human OB(Obestatin) ELISA Kit |
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EH2063 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human CMA1(Chymase) ELISA Kit |
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EH2077 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human ENHO(Adropin) ELISA Kit |
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EH2290 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human CNX(Calnexin) ELISA Kit |
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EH2856 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml |
Human CPP(Copeptin) ELISA Kit |
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EH2880 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human MT(Melatonin) ELISA Kit |
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EH3344 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pg/ml |
Human Pax(Paxillin) ELISA Kit |
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EH3511 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human PDCN(Podocin) ELISA Kit |
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EH3529 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human TPS(Tryptase) ELISA Kit |
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EH3906 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
Human ENG(Endoglin) ELISA Kit |
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EH0071 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human GHRL(Ghrelin) ELISA Kit |
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EH0355 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 28.125pg/ml |
Human COR(Cortisol) ELISA Kit |
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EH0641 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.234 ng/ml |
Human CAT(Catalase) ELISA Kit |
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EH0643 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human STH(Saitohin) ELISA Kit |
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EH0832 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human GSN(Gelsolin) ELISA Kit |
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EH0875 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 3.75 ng/ml |
Human VIM(Vimentin) ELISA Kit |
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EH1166 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688 ng/ml |
Human ASPN(Asporin) ELISA Kit |
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EH1174 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human S100 Protein ELISA Kit |
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EH4865 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human Histone-H3 ELISA Kit |
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EH9123 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml |
Human CFP(Properdin) ELISA Kit |
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EH1217 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human HRNR(Hornerin) ELISA Kit |
|||
EH1240 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human RNLS(Renalase) ELISA Kit |
|||
EH1250 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml |
Human MYOG(Myogenin) ELISA Kit |
|||
EH1256 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml |
Human STOM(Stomatin)ELISA Kit |
|||
EH12686 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human FLG(Filaggrin) ELISA Kit |
|||
EH1353 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human LGMN(Legumain) ELISA Kit |
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EH1372 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human SPAST(Spastin) ELISA Kit |
|||
EH15353 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human OCLN(Occludin) ELISA Kit |
|||
EH1674 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human NEO1(Neogenin) ELISA Kit |
|||
EH1782 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human Opi(Opiorphin) ELISA Kit |
|||
EH1927 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human HPX(Hemopexin) ELISA Kit |
|||
EH2031 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human UCN(Urocortin) ELISA Kit |
|||
EH2157 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
Human UTRN(Utrophin) ELISA Kit |
|||
EH2376 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml |
Human HDLBP(Vigilin) ELISA Kit |
|||
EH2505 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human his(Histamine) ELISA Kit |
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EH2552 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
Human Amylase Alpha ELISA Kit |
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EH2652 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.4mIU/ml |
Human ARO(Aromatase) ELISA Kit |
|||
EH2665 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Schistosomes within the Lung: Immunobiology and Alternative
Schistosome an infection is a significant trigger of world morbidity, significantly in sub-Saharan Africa. Nevertheless, there isn’t a efficient vaccine for this main uncared for tropical illness, and re-infection routinely happens after chemotherapeutic therapy. Following invasion by way of the pores and skin, larval schistosomula enter the circulatory system and migrate by way of the lung earlier than maturing to maturity within the mesenteric or urogenital vasculature.
Eggs launched from grownup worms can develop into trapped in numerous tissues, with resultant inflammatory responses resulting in hepato-splenic, intestinal, or urogenital illness – processes which have been extensively studied lately.
In distinction, though lung pathology can happen in each the acute and persistent phases of schistosomiasis, the mechanisms underlying pulmonary illness are significantly poorly understood. In persistent an infection, egg-mediated fibrosis and vascular destruction can result in the formation of portosystemic shunts by way of which eggs can embolise to the lungs, the place they will set off granulomatous illness.
Acute schistosomiasis, or Katayama syndrome, which is primarily evident in non-endemic people, happens throughout pulmonary larval migration, maturation, and preliminary egg-production, usually involving fever and a cough with an accompanying immune cell infiltrate into the lung. Importantly, lung migrating larvae usually are not only a reason for irritation and pathology however are a key goal for future vaccine design.
Nevertheless, vaccine efforts are hindered by a restricted understanding of what constitutes a protecting immune response to larvae. On this evaluation, we discover the present understanding of pulmonary immune responses and inflammatory pathology in schistosomiasis, highlighting necessary unanswered questions and areas for future analysis.
Immunobiology and nanotherapeutics of extreme acute respiratory syndrome 2 (SARS-CoV-2): a present replace
The emergence of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) constitutes probably the most vital world public well being problem in a century. It has reignited analysis curiosity in coronavirus.
- Whereas little info is out there, analysis is at the moment in progress to comprehensively perceive the overall biology and immune response mechanism in opposition to SARS-CoV-2. The spike proteins (S protein) of SARS-CoV-2 carry out an important perform in viral an infection institution. ACE2 and TMPRSS2 play a pivotal position in viral entry. “
- Upon viral entry, the launched pro-inflammatory proteins (cytokines and chemokines) trigger the migration of the T cells, monocytes, and macrophages to the an infection website.
- IFNϒ launched by T cells initiates a loop of pro-inflammatory suggestions. The inflammatory state could additional improve with a rise in immune dysfunction chargeable for the an infection’s development.
- A therapy strategy that stops ACE2-mediated viral entry and reduces inflammatory response is an important therapeutic intervention technique, and nanomaterials and their conjugates are promising candidates. Nanoparticles can inhibit viral entry and replication.
- Nanomaterials have additionally discovered utility in focused drug supply and in addition in growing a vaccine in opposition to SARS-CoV-2. Right here, we briefly summarize the origin, transmission, and scientific options of SARS-CoV-2. We then mentioned the immune response mechanisms of SARS-CoV-2.
- Lastly, we additional mentioned nanotechnology’s potentials as an intervention technique in opposition to SARS-CoV-2 an infection. All these understandings can be essential in growing therapeutic methods in opposition to SARS-CoV-2.
PD-1 immunobiology in glomerulonephritis and renal cell carcinoma
Background: Programmed cell loss of life protein (PD)-1 receptors and ligands on immune cells and kidney parenchymal cells assist preserve immunological homeostasis within the kidney. Dysregulated PD-1:PD-L1 binding interactions happen in the course of the pathogenesis of glomerulopathies and renal cell carcinoma (RCC). The regulation of those molecules within the kidney is necessary to PD-1/PD-L1 immunotherapies that deal with RCC and should induce glomerulopathies as an hostile occasion.
Strategies: The expression and performance of PD-1 molecules on immune and kidney parenchymal cells had been reviewed within the wholesome kidney, PD-1 immunotherapy-induced nephrotoxicity, glomerulopathies and RCC.
Outcomes: PD-1 and/or its ligands are expressed on kidney macrophages, dendritic cells, lymphocytes, and renal proximal tubule epithelial cells. Vitamin D3, glutathione and AMP-activated protein kinase (AMPK) regulate hypoxic cell indicators concerned within the expression and performance of PD-1 molecules.
These pathways are altered in kidney illness and are linked to the manufacturing of vascular endothelial progress issue, erythropoietin, adiponectin, interleukin (IL)-18, IL-23, and chemokines that bind CXCR3, CXCR4, and/or CXCR7.
These elements are differentially produced in glomerulonephritis and RCC and could also be necessary biomarkers in sufferers that obtain PD-1 therapies and/or develop glomerulonephritis as an hostile occasion CONCLUSION: By evaluating the features of the PD-1 axis in glomerulopathies and RCC, we recognized related chemokines concerned within the recruitment of immune cells and distinct mediators in T cell differentiation.
The expression and performance of PD-1 and PD-1 ligands in diseased tissue and significantly on double-negative T cells and parenchymal kidney cells wants continued exploration. The potential regulation of the PD-1 axis by vitamin D3, glutathione and/or AMPK cell indicators could also be necessary to kidney illness and the PD-1 immunotherapeutic response.
293AAV Cell Line |
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AAV-100 | Cell Biolabs | 1 vial | EUR 405 |
293LTV Cell Line |
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LTV-100 | Cell Biolabs | 1 vial | EUR 405 |
293RTV Cell Line |
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RV-100 | Cell Biolabs | 1 vial | EUR 405 |
MCF7 [MCF-7] Cell Line |
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CL-0149 | Elabscience Biotech | 1×10⁶ cells/vial | EUR 420 |
Description: Homo sapiens, Human |
293/GFP Cell Line |
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AKR-200 | Cell Biolabs | 1 vial | EUR 460 |
T47D/GFP Cell Line |
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AKR-208 | Cell Biolabs | 1 vial | EUR 686.4 |
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
A549/GFP Cell Line |
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AKR-209 | Cell Biolabs | 1 vial | EUR 460 |
HeLa/GFP Cell Line |
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AKR-213 | Cell Biolabs | 1 vial | EUR 460 |
293/Cas9 Cell Line |
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AKR-5110 | Cell Biolabs | 1 vial | EUR 460 |
HeLa/Cas9 Cell Line |
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AKR-5111 | Cell Biolabs | 1 vial | EUR 460 |
NIH3T3/GFP Cell Line |
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AKR-214 | Cell Biolabs | 1 vial | EUR 460 |
NIH3T3/Cas9 Cell Line |
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AKR-5104 | Cell Biolabs | 1 vial | EUR 460 |
OVCAR-5/RFP Cell Line |
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AKR-254 | Cell Biolabs | 1 vial | EUR 686.4 |
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line. |
MCF-7-LUC cells |
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S0006002 | Addexbio | One Frozen vial | EUR 420 |
PKCa Stable Expressing MCF-7 (MCF-7/PKCa20) Cell Line |
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T6115 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Platinum-E Retroviral Packaging Cell Line, Ecotropic |
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RV-101 | Cell Biolabs | 1 vial | EUR 770 |
Platinum-GP Retroviral Packaging Cell Line, Pantropic |
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RV-103 | Cell Biolabs | 1 vial | EUR 770 |
Platinum-A Retroviral Packaging Cell Line, Amphotropic |
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RV-102 | Cell Biolabs | 1 vial | EUR 770 |
Total Protein - Murine Embryonic Stem Cell Line D3 |
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CBA-305 | Cell Biolabs | 500 ?g | EUR 414 |
Description:
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MCF 10A Cell Line |
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CL-0525 | Elabscience Biotech | 1×10⁶ cells/vial | EUR 500 |
Description: Homo sapiens, Human |
cDNA - Human Tumor Cell Line: MCF 7 |
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C1255830 | Biochain | 40 reactions | EUR 424 |
Flavopiridol-Resistant MCF-7 Cell Line (FLV100) |
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T8033 | ABM | 1x10^6 cells / 1.0 ml | EUR 2950 |
Flavopiridol-Resistant MCF-7 Cell Line (FLV1000) |
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T8035 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
Luc-Akt-PH Stable MCF7 Cell Line |
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T3160 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Total RNA - Human Tumor Cell Line: MCF 7 |
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R1255830-50 | Biochain | 50 ug | EUR 229 |
Genomic DNA - Human Tumor Cell Line: MCF 7 |
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D1255830 | Biochain | 100 ug | EUR 282 |
Total Protein - Human Tumor Cell Line: MCF 7 |
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P1255830 | Biochain | 1 mg | EUR 216 |
Membrane Protein - Human Tumor Cell Line: MCF 7 |
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P3255830 | Biochain | 0.1 mg | EUR 311 |
Exosome derived from human breast cancer, noninvasive cell line (MCF-7 cell line) |
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Exo-CH06 | Creative BioMart | Each | EUR 1249.5 |
Description: Exosome |
Paraffin Tissue Section - Human Tumor Cell Line: MCF-7 |
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T2255830 | Biochain | 5 slides | EUR 262 |
AAV2-Luc Control Virus |
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AAV-320 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 2. |
AAV1-Luc Control Virus |
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AAV-321 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 1. |
AAV3-Luc Control Virus |
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AAV-323 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 3. |
AAV4-Luc Control Virus |
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AAV-324 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 4. |
AAV5-Luc Control Virus |
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AAV-325 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 5. |
AAV6-Luc Control Virus |
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AAV-326 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 6. |
Tissue, Section, Human Disease, Human Tumor Cell Line, MCF-7 (Paraffin) |
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MBS640859-5Slides | MyBiosource | 5Slides | EUR 510 |
Tissue, Section, Human Disease, Human Tumor Cell Line, MCF-7 (Paraffin) |
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MBS640859-5x5Slides | MyBiosource | 5x5Slides | EUR 2145 |
GAS(Luc) Report Cell Line-HeLa |
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ABC-RC099D | AcceGen | 1 vial | Ask for price |
Description: The GAS reporter (Luc)-HeLa cell line is designed to monitor the activity of IFN gamma-induced signal transduction pathways in cultured cells by measuring activated STAT1 homodimers. It contains a firefly luciferase gene driven by three copies of the IFN gamma-activated sites (GAS) located upstream of the minimal TATA promoter. IFNγ first binds to a heterodimeric receptor consisting of two chains, IFNGR1 and IFNGR2, causing its dimerization and the activation of specific Janus family kinases (JAK1 and JAK2). Two STAT1 molecules associate with this ligand-activated receptor complex and are activated by phosphorylation to form active homodimer. The active STAT1 homodimers translocate to the nucleus where they bind IFN gamma-activated sites (GAS) in the promoter of IFNγ inducible genes, including luciferase reporter gene. |
GAL4 Report Cell Line(Luc)-HEK293 |
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ABC-RC113D | AcceGen | 1 vial | Ask for price |
Description: The GAL4 Reporter (Luc) andndash; HEK293 Cell Line contains a firefly luciferase gene under the control of a multimerized GAL4 upstream activation sequence (UAS) stably integrated into HEK293 cells. The cell line does not contain any exogenous activators of the GAL4 reporter. |
NFAT Reporter (Luc) - Jurkat Cell Line |
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60621 | BPS Bioscience | 2 vials | EUR 2295 |
Description: The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the_x000D_NFAT response element stably integrated into Jurkat cells. This cell line has been validated for_x000D_response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as_x000D_a control cell line for other NFAT reporter cell lines expressing various immune checkpoint_x000D_receptors. |
GAL4 Reporter (Luc)-HEK293 Cell Line |
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60656 | BPS Bioscience | 2 vials | EUR 1095 |
Description: The GAL4 Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of a multimerized GAL4 upstream activation sequence (UAS) stably integrated into HEK293 cells. The cell line does not contain any exogenous activators of the GAL4 reporter and can be used alongside BPS Cat. #60655 as a control. |
Foxp3(Luc) Report Cell Line-Jurkat |
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ABC-RC106D | AcceGen | 1 vial | Ask for price |
Description: Human Foxp3 luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by a human Foxp3 promoter and an enhancer-like conserved noncoding sequence upstream of the Foxp3 promoter. |
MCF-7 Human breast cancer, noninvasive cell line: >1x10^10 frozen exosomes |
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EXOP-100A-1 | SBI | 50 ug | EUR 409 |
STAT5 Reporter (Luc) - Ba/F3 Cell line |
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79772 | BPS Bioscience | 2 vials | EUR 2275 |
Description: The STAT5 Reporter (Luc)-Ba/F3 cell line is designed for monitoring STAT5 signal transduction pathways. It contains a firefly luciferase gene driven by the STAT5 response element located upstream of the minimal TATA promoter. After activation by cytokines or growth factors, endogenous STAT5 binds to the DNA response elements, inducing transcription of the luciferase reporter gene. |
StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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CBA-325 | Cell Biolabs | 96 assays | EUR 1027.2 |
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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CBA-325-5 | Cell Biolabs | 5 x 96 assays | EUR 4033.2 |
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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CBA-135 | Cell Biolabs | 96 assays | EUR 715 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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CBA-135-5 | Cell Biolabs | 5 x 96 assays | EUR 3095 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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CBA-140 | Cell Biolabs | 96 assays | EUR 750 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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CBA-140-5 | Cell Biolabs | 5 x 96 assays | EUR 3215 |
IRF Reporter (Luc) - THP-1 Cell line |
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79858 | BPS Bioscience | 2 vials | EUR 1810 |
Description: The Interferon Regulatory Factor (IRF) reporter (Luc)-THP-1 cell line is designed to study the activation and signaling of Cytosolic DNA Sensors (CDS) in human monocytic cell line THP-1. It contains a firefly luciferase gene driven by multimerized ISRE (Interferon Stimulated Response Element) located upstream of the minimal TATA promoter. _x000D_The cGAS-STING pathway acts to detect cytosolic DNA and induce an immune response. Briefly, upon binding DNA, the protein cGAS (cyclic GMP-AMP Synthase) triggers reaction of GTP and ATP to form cGAMP. cGAMP binds to STING (Stimulator of Interferon Genes) which triggers phosphorylation of IRF3 via TBK1. IRF3 can then bind to interferon-stimulated responsive elements (ISRE) in the nucleus and leads to IFN-α/β production. The IRF reporter (Luc)-THP-1 cell line is highly responsive to STING and CDS ligands. |
GR-GAL4 Report Cell Line(Luc)-HEK293 |
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ABC-RC114D | AcceGen | 1 vial | Ask for price |
Description: The Glucocorticoid Receptor Pathway GAL4 Reporter (Luc) – HEK293 Cell Line contains a firefly luciferase gene under the control of glucocorticoid receptor ligand binding domain that is fused to the DNA binding domain (DBD) of GAL4 (GAL4 DBD-GR) stably integrated into HEK293 cells. This fusion construct activates firefly luciferase expression under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low cross-reactivity for other nuclear receptor pathways. This cell line is validated for response to stimulation of DXMS and to the treatment with mifepristone, an inhibitor of the glucocorticoid signaling pathway. |
NF-κB Reporter (Luc) - HCT116 Cell Line |
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60623 | BPS Bioscience | 2 vials | EUR 1095 |
Description: NF-B luciferase reporter construct is stably integrated into the genome of HCT-116 cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene._x000D_The NF-κB-luciferase/HCT-116 cell line is suitable for monitoring the activity of NF-κB signaling in response to stimulants such as the cytokines TNF and IL-1β, pathogen-associated molecular pattern (PAMP) (i.e. flagellin) or endogenous damage-associated molecular pattern (DAMP) molecules (i.e. NOD1 ligand) (see application references). It is also suitable for establishing cell-based screens for inhibitors that target specific NF-κB stimulating molecules. This cell line can be further modified to allow investigation of downstream NF-κB activities as a result of targeted genetic mutation(s). |
NF-κB reporter (Luc) - HEK293 Cell line |
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60650 | BPS Bioscience | 2 vials | EUR 1365 |
Description: The NF-κB reporter (Luc) HEK293 cell line is designed to monitor nuclear factor Kappa B (NF-κB) activity. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or agonists of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. The cell line has been functionally validated in response to human TNF-α, IL-1β, and IL-17. |
NF-kB reporter (Luc) - HEK293 Cell line |
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GWB-PS76F8 | GenWay Biotech | 2X10(6)cells | Ask for price |
CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size |
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CBA-135-T | Cell Biolabs | 24 assays | EUR 518.4 |
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
Tissue, Total Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima) |
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MBS657022-1mg | MyBiosource | 1mg | EUR 565 |
Tissue, Total Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima) |
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MBS657022-5x1mg | MyBiosource | 5x1mg | EUR 2315 |
CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size |
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CBA-140-T | Cell Biolabs | 24 assays | EUR 547.2 |
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
STAT3 Reporter (Luc) - HEK293 Cell line (Puromycin) |
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79800-P | BPS Bioscience | 2 vials | EUR 3730 |
Description: The STAT3 Reporter (Luc)-HEK293 cell line is designed for monitoring STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines and growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the luciferase reporter gene. |
Luciferase Stable 17L3C (17L3C-luc) Cell Line |
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T6240 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Tissue, Membrane Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima) |
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MBS639777-01mg | MyBiosource | 0.1mg | EUR 570 |
Tissue, Membrane Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima) |
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MBS639777-5x01mg | MyBiosource | 5x0.1mg | EUR 2345 |
Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line |
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60628 | BPS Bioscience | 2 vials | EUR 7645 |
Description: Human Foxp3 luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by a human Foxp3 promoter and an enhancer-like conserved noncoding sequence upstream of the Foxp3 promoter. |
NF- κB Reporter (Luc) - Raw 264.7 Cell line |
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79978 | BPS Bioscience | 2 vials | EUR 2045 |
Description: The NF-κB reporter (Luc)-Raw 264.7 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. |
Collagen-based Cell Contraction Assay |
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CBA-201 | Cell Biolabs | 24 assays | EUR 420 |
PAI-1 Report Cell Line (Luc)-Mv1 Lu |
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ABC-RC199D | AcceGen | 1 vial | Ask for price |
Description: PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor β (TGF-β)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-β (TGF-β) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression.PAI-1 Reporter (Luc) –Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity. |
NF- κB Reporter (Luc) - THP-1 Cell Line |
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79645 | BPS Bioscience | 2 vials | EUR 1900 |
Description: The NF-κB reporter (Luc)-THP-1 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. |
Radius 384-Well Cell Migration Assay |
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CBA-127 | Cell Biolabs | 384 assays | EUR 721.2 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
Radius 384-Well Cell Migration Assay |
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CBA-127-5 | Cell Biolabs | 5 x 384 wells | EUR 2802 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
PAI-1 Reporter (Luc) - Mv1 Lu Cell Line |
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60544 | BPS Bioscience | 2 vials | EUR 3595 |
Description: PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor β (TGF-β)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-β (TGF-β) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression._x000D__x000D_PAI-1 Reporter (Luc) -Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity. _x000D_ |
NF-κB reporter (Luc) - NIH/3T3 Cell line |
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79469 | BPS Bioscience | 2 vials | EUR 1900 |
Description: The NF-κB reporter (Luc)-NIH/3T3 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. |
HIF-1 Alpha Cell Based ELISA Kit |
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CBA-281 | Cell Biolabs | 96 assays | EUR 734.4 |
Description: Cell Biolabs? HIF-1 Cell Based ELISA Kit is an immunoassay developed for rapid detection of HIF-1 Alpha in fixed cells. Cells on a microplate are stimulated for HIF-1 Alpha stabilization, fixed, permeabilized, and then neutralized in the well. HIF-1 Alpha is then detected with an anti-HIF-1 alpha antibody followed by an HRP conjugated secondary antibody. Each kit provides sufficient reagents to perform up to a total of 96 assays and can detect HIF-1 Alpha from human, mouse, or rat. |
CytoSelect™ MTT Cell Proliferation Assay |
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CBA-252 | Cell Biolabs | 960 assays | EUR 320 |
NF-κB Reporter (Luc) - CHO-K1 Cell Line |
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60622 | BPS Bioscience | 2 vials | EUR 1095 |
Description: An NF-κB luciferase reporter construct is stably integrated into the genome of CHO-K1 cells. The firefly luciferase gene is controlled by the NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene._x000D_The NF-κB-luciferase / CHO-K1 cell line is suitable for monitoring the activity of NF-κB transcription factor through luminescence readout.). This cell line responds to human cytokine IL-1β, responds moderately to human TNF, and does not respond to human IFN-λ (2 µg/ml). Reducing the amount of serum during incubation period may increase the sensitivity to cytokines. Since CHO-K1 cells do not express endogenous human proteins, this cell line provides an excellent platform to enable exogenous expression of a protein of interest to study its downstream effect on NF-κB signaling. |
CD40/NF-κB Report Cell Line(Luc) - HEK293 |
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ABC-RC111D | AcceGen | 1 vial | Ask for price |
Description: Recombinant HEK293 cell line expressing full length human CD40 (Tumor necrosis factor receptor superfamily member 5; TNFRSF5). Expression is confirmed by real-time qPCR and Western Blot. This NF-ĸB luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-andkappa;B response element located upstream of the TATA promoter. Following activation by human CD40 ligand, NF-ĸB transcription factor binds to the DNA response elements to induce transcription of the luciferase gene. |
Radius™ 24-Well Cell Migration Assay |
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CBA-125 | Cell Biolabs | 24 assays | EUR 425 |
Radius™ 24-Well Cell Migration Assay |
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CBA-125-5 | Cell Biolabs | 5 x 24 assays | EUR 1820 |
Radius™ 96-Well Cell Migration Assay |
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CBA-126 | Cell Biolabs | 96 assays | EUR 495 |
Radius™ 96-Well Cell Migration Assay |
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CBA-126-5 | Cell Biolabs | 5 x 96 assays | EUR 2095 |
Radius™ 48-Well Cell Migration Assay |
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CBA-5037 | Cell Biolabs | 48 assays | EUR 445 |
Radius™ 48-Well Cell Migration Assay |
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CBA-5037-5 | Cell Biolabs | 5 x 48 assays | EUR 1895 |
NF-κB Reporter (Luc) - A549 Stable Cell Line |
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60625 | BPS Bioscience | 2 vials | EUR 1915 |
Description: NF-κB luciferase reporter construct is stably integrated into the genome of A549 cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene. |
STAT5 Reporter (Luc)- U937 Cell Line (GM-CSF) |
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79941 | BPS Bioscience | 2 vials | EUR 1980 |
Description: The STAT5 Reporter (Luc)-U937 cell line is designed for monitoring STAT5 signal transduction pathway in the U937 cell line. It contains a firefly luciferase gene driven by the STAT5 response element located upstream of the minimal TATA promoter. After activation by GM-CSF, endogenous STAT5 binds to the DNA response elements, inducing transcription of the luciferase reporter gene. |
CytoSelect Cell Proliferation Assay Reagent (Fluorometric) |
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CBA-250 | Cell Biolabs | 10 mL | EUR 490.8 |
Description: Cell Biolabs? CytoSelect Cell Proliferation Assay Reagent (Fluorometric) provides a fluorometric format for measuring and monitoring cell proliferation. Cells can be plated and then treated with compounds or agents that affect proliferation. Cells are then incubated with the proliferation reagent. Upon entering metabolically active live cells, the non-fluorescent proliferation reagent is converted into a bright red fluorescent form. An increase in cell proliferation is accompanied by increased fluorescent signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions. The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues. This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. The kit contains sufficient reagents for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates. |
CytoSelect™ BrdU Cell Proliferation ELISA Kit |
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CBA-251 | Cell Biolabs | 96 assays | EUR 455 |
CytoSelect™ 96-well Cell Transformation Assay |
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CBA-130 | Cell Biolabs | 96 assays | EUR 640 |
CytoSelect™ 96-well Cell Transformation Assay |
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CBA-130-5 | Cell Biolabs | 5 x 96 assays | EUR 2695 |
CytoSelect™ Cell Viability and Cytotoxicity Assay |
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CBA-240 | Cell Biolabs | 96 assays | EUR 305 |
Tissue, Total RNA, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinoma), BioGenomics |
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MBS638573-005mg | MyBiosource | 0.05mg | EUR 485 |
Tissue, Total RNA, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinoma), BioGenomics |
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MBS638573-5x005mg | MyBiosource | 5x0.05mg | EUR 1960 |
CytoSelect 24-well Laminin Cell Invasion, Colorimetric |
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CBA-110-LN | Cell Biolabs | 12 assays | EUR 714 |
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin. |
CytoSelect™ 24-Well Cell Co-Culture System |
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CBA-160 | Cell Biolabs | 24 assays | EUR 365 |
CytoSelect™ 24-Well Cell Co-Culture System |
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CBA-160-5 | Cell Biolabs | 5 x 24 assays | EUR 1585 |
CytoSelect™ 48-Well Cell Contraction Assay Kit |
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CBA-5021 | Cell Biolabs | 48 assays | EUR 575 |
CytoSelect 384-well Cell Transformation Assay, Fluorometric |
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CBA-145 | Cell Biolabs | 384 assays | EUR 1208.4 |
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader. |
CytoSelect 384-well Cell Transformation Assay, Fluorometric |
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CBA-145-5 | Cell Biolabs | 5 x 384 assays | EUR 4681.2 |
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader. |
CytoSelect™ Cell Proliferation Assay Reagent (Colorimetric) |
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CBA-253 | Cell Biolabs | 10 mL | EUR 320 |
Radius 24-Well Cell Migration Assay, (Laminin Coated) |
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CBA-125-LN | Cell Biolabs | 24 assays | EUR 714 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |